Gluten-Free Cheeseburger Biscuit Casserole
This hearty casserole combines all the flavors of a classic cheeseburger in comfort food form. Ground beef is simmered with onions, tomatoes, ketchup, and mustard, then topped with melted cheddar cheese and fluffy biscuit quarters. Perfect for busy weeknight dinners or casual family gatherings, this one-dish meal delivers familiar flavors with minimal cleanup. The biscuit topping bakes to golden perfection while absorbing some of the savory beef juices below.
Ingredients
Instructions
- 1
Preheat oven to 375°F
- 2
Cook ground beef and onion in skillet over medium heat until beef is browned and drain excess fat
- 3
Add diced tomatoes, ketchup, and mustard to skillet and stir to combine
- 4
Simmer mixture for a few minutes
- 5
Transfer beef mixture to baking dish
- 6
Sprinkle shredded cheddar cheese on top
- 7
Place biscuit dough quarters evenly over cheese layer
- 8
Bake for 25-30 minutes until biscuits are golden brown and cooked through
- 9
Let casserole cool for a few minutes before serving
Tips
Drain excess fat from the beef to prevent a greasy casserole bottom.
Cut biscuit dough into quarters for better coverage and even baking.
Let the casserole rest before serving to help it set and make cutting easier.
Good to Know
Refrigerate leftovers for up to 3 days in an airtight container.
Can assemble casserole up to 24 hours ahead and refrigerate before baking.
Serve hot directly from the baking dish with a spatula.
Common Mistakes
Don't skip draining the beef fat or the casserole will be greasy.
Don't overbake the biscuits or they'll become dry and tough.
Substitutions
Dairy-Free Swaps
General Alternatives
FAQ
Can I use frozen biscuit dough?
Yes, thaw completely first and cut into quarters as directed for even baking.
What if I don't have ketchup?
Substitute with tomato sauce mixed with a tablespoon of brown sugar for similar sweetness.
How long will leftovers keep?
Refrigerate for up to 3 days or freeze portions for up to 2 months in freezer-safe containers.