Cheesy Cheddar Chicken Spaghetti Casserole with Creamy Sauce
A hearty baked pasta casserole combining tender spaghetti with seasoned chicken in a rich, creamy sauce made from cream of chicken soup and sour cream. Sharp cheddar cheese melts throughout while a golden parmesan breadcrumb topping adds texture. Perfect for family dinners or potluck gatherings, this comforting dish delivers classic flavors in an easy one-dish format that feeds a crowd.
Ingredients
- 1 package spaghetti, broken, 12 ounce
- 3 cups chicken, cubed cooked, rotisserie works great
- 2 can condensed cream of chicken soup, 10 3/4, undiluted
- 1 container sour cream, 16 oz
- 1 cup chicken broth
- 1 teaspoon seasoning salt
- ¼ teaspoon pepper
- ⅛ teaspoon cayenne pepper
- 2 Tablespoons dried parsley
- 2 cups sharp cheddar cheese
- ½ cup Italian Seasoned Bread Crumbs
- ½ cup parmesan cheese, grated
Instructions
- 1
Preheat oven to 350 degrees and spray a 9x13 pan with cooking spray
- 2
Cook pasta according to package directions until al dente and drain
- 3
Combine cream of chicken soup, sour cream, chicken broth, seasoning salt, pepper, cayenne pepper, and dried parsley in a large bowl
- 4
Add cooked spaghetti and chicken to the sauce mixture and toss until coated
- 5
Place mixture in the prepared pan and top with sharp cheddar cheese
- 6
Combine parmesan cheese and bread crumbs and sprinkle on top
- 7
Cover with foil and bake for 40-45 minutes
- 8
Remove foil for the last ten minutes to make bubbly
Tips
Use rotisserie chicken for convenience or leftover cooked chicken works perfectly in this recipe.
Breaking the spaghetti in half before cooking makes the casserole easier to serve and eat.
Let the casserole rest for 5-10 minutes after baking to allow the sauce to set before serving.
Good to Know
Refrigerate leftovers for up to 3-4 days in covered container
Assemble casserole up to 1 day ahead, cover and refrigerate, add 10-15 minutes to baking time
Serve hot directly from the baking dish with a side salad or steamed vegetables
Common Mistakes
Don't overcook the pasta initially as it will continue cooking in the oven
Cover with foil to prevent excessive browning of the cheese topping
Substitutions
Gluten-Free Swaps
General Alternatives
FAQ
Can I freeze this casserole?
Yes, assemble without baking, wrap tightly and freeze up to 3 months. Thaw overnight in refrigerator before baking as directed.
What if I don't have seasoning salt?
Substitute with 3/4 teaspoon regular salt plus 1/4 teaspoon garlic powder and onion powder for similar flavor.
How long will leftovers keep?
Refrigerated leftovers stay fresh for 3-4 days. Reheat individual portions in microwave or warm covered in 350°F oven.