Gluten-Free Impossibly Easy Pizza Bake with Pepperoni

A clever layered casserole that creates its own crust as it bakes, combining tender Bisquick dumplings with classic pizza flavors. The impossibly easy technique means no rolling or shaping - just drop spoonfuls of dough that puff and merge during baking. Perfect for busy weeknight dinners or when you want pizza comfort without the fuss. The gluten-free version delivers all the cheesy, saucy satisfaction of the original.
Ingredients
- ⅓ cup shortening
- 2 cups Bisquick Gluten Free pancake and baking mix
- ⅝ cup milk
- 3 eggs
- 1 jar (14 oz) pizza sauce
- 1 package (7 oz) gluten-free pepperoni, sliced
- 1 bag (8 oz) mozzarella cheese, shredded
Instructions
- 1
Heat oven to 375°F and spray 13x9-inch glass baking dish with cooking spray
- 2
Cut shortening into Bisquick mix with fork until particles are size of small peas
- 3
Stir in milk and eggs until soft dough forms
- 4
Drop half of dough by spoonfuls evenly in bottom of baking dish
- 5
Drizzle about 1 cup pizza sauce over dough
- 6
Arrange half of the pepperoni slices evenly over sauce
- 7
Top with 1 cup of the cheese
- 8
Repeat layers with remaining dough, pizza sauce, pepperoni and cheese
- 9
Bake 22 to 26 minutes or until golden brown, biscuits in center are cooked and cheese in center is bubbly
Tips
Don't worry if the first layer of dough doesn't cover the entire bottom - it will spread and puff as it bakes to form the base.
Let the casserole rest for 5 minutes after baking to allow the layers to set before serving.
Use a glass baking dish for even browning and to easily see when the bottom layer is golden.
Good to Know
Refrigerate leftovers up to 3 days. Reheat individual portions in microwave.
Can be assembled up to 4 hours ahead and refrigerated before baking.
Cut into squares and serve hot. Pairs well with a simple green salad.
Common Mistakes
Don't overmix the dough to avoid tough biscuits.
Use cooking spray to prevent sticking in glass dish.
Check center doneness with knife to avoid undercooked dough.
Substitutions
FAQ
Can I use regular Bisquick mix instead?
Yes, substitute regular Bisquick mix 1:1 if gluten-free isn't needed. The texture and cooking time remain the same.
What if I don't have shortening?
Butter works well as a substitute. Use the same amount but expect slightly richer flavor and more tender texture.
How long does this keep in the refrigerator?
Store covered for up to 3 days. Reheat portions in the microwave or cover and warm in a 350°F oven.