Gluten-Free Impossibly Easy Pizza Bake with Pepperoni

Prep: 15 minCook: 24 min8 servingsmedium
Gluten-Free Impossibly Easy Pizza Bake with Pepperoni

A clever layered casserole that creates its own crust as it bakes, combining tender Bisquick dumplings with classic pizza flavors. The impossibly easy technique means no rolling or shaping - just drop spoonfuls of dough that puff and merge during baking. Perfect for busy weeknight dinners or when you want pizza comfort without the fuss. The gluten-free version delivers all the cheesy, saucy satisfaction of the original.

Ingredients

8 servings
  • cup shortening
    butter1:1gluten-freeadds dairy

    adds richness

    Full guide →
  • 2 cups Bisquick Gluten Free pancake and baking mix
  • cup milk
  • 3 eggs
  • 1 jar (14 oz) pizza sauce
    marinara sauce1:1gluten-freevegetarian

    similar base

    Full guide →
  • 1 package (7 oz) gluten-free pepperoni, sliced
    Italian sausage1:1gluten-freemeat

    cook first

    Full guide →
  • 1 bag (8 oz) mozzarella cheese, shredded
    cheddar cheese1:1gluten-freevegetarian

    sharper flavor

    Full guide →

Instructions

  1. 1

    Heat oven to 375°F and spray 13x9-inch glass baking dish with cooking spray

  2. 2

    Cut shortening into Bisquick mix with fork until particles are size of small peas

  3. 3

    Stir in milk and eggs until soft dough forms

  4. 4

    Drop half of dough by spoonfuls evenly in bottom of baking dish

  5. 5

    Drizzle about 1 cup pizza sauce over dough

  6. 6

    Arrange half of the pepperoni slices evenly over sauce

  7. 7

    Top with 1 cup of the cheese

  8. 8

    Repeat layers with remaining dough, pizza sauce, pepperoni and cheese

  9. 9

    Bake 22 to 26 minutes or until golden brown, biscuits in center are cooked and cheese in center is bubbly

Tips

Tip 1

Don't worry if the first layer of dough doesn't cover the entire bottom - it will spread and puff as it bakes to form the base.

Tip 2

Let the casserole rest for 5 minutes after baking to allow the layers to set before serving.

Tip 3

Use a glass baking dish for even browning and to easily see when the bottom layer is golden.

Good to Know

Storage

Refrigerate leftovers up to 3 days. Reheat individual portions in microwave.

Make Ahead

Can be assembled up to 4 hours ahead and refrigerated before baking.

Serve With

Cut into squares and serve hot. Pairs well with a simple green salad.

See pairing guide →

Common Mistakes

Watch

Don't overmix the dough to avoid tough biscuits.

Watch

Use cooking spray to prevent sticking in glass dish.

Watch

Check center doneness with knife to avoid undercooked dough.

Substitutions

shortening
butter1:1gluten-freeadds dairy

adds richness

Full guide →
pizza sauce
marinara sauce1:1gluten-freevegetarian

similar base

Full guide →
pepperoni
Italian sausage1:1gluten-freemeat

cook first

Full guide →
mozzarella
cheddar cheese1:1gluten-freevegetarian

sharper flavor

Full guide →
Find more substitutions →

FAQ

Can I use regular Bisquick mix instead?

Yes, substitute regular Bisquick mix 1:1 if gluten-free isn't needed. The texture and cooking time remain the same.

What if I don't have shortening?

Butter works well as a substitute. Use the same amount but expect slightly richer flavor and more tender texture.

How long does this keep in the refrigerator?

Store covered for up to 3 days. Reheat portions in the microwave or cover and warm in a 350°F oven.