Gluten-Free Ground Beef Pizza Casserole

Prep: 15 minCook: 30 min6 servingsmediumAmerican
Ground Beef Pizza Casserole with Golden Biscuits

A hearty family-friendly casserole that transforms classic pizza flavors into a comforting baked dish. Seasoned ground beef mingles with pizza sauce, bell peppers, and onions, topped with melted mozzarella and fluffy golden biscuits that bake right on top. Perfect for busy weeknight dinners when you want pizza satisfaction without the fuss of making dough. The biscuits create a satisfying bread component while soaking up the savory flavors below, making this a complete meal in one dish.

Ingredients

6 servings
  • 1 lb ground beef
    ground turkey1:1leaner

    reduces fat content

    Full guide →
  • 1 can pizza sauce
    marinara sauce1:1basic

    similar flavor profile

    Full guide →
  • 1 cup mozzarella cheese, shredded
    cheddar cheese1:1flavor

    sharper taste

    Full guide →
  • 1 can refrigerated biscuits
    frozen biscuits1:1convenience

    thaw first

  • 1 cup bell peppers, chopped
  • 1 cup onions, chopped

Instructions

  1. 1

    Preheat oven to 375°F

  2. 2

    Cook ground beef in skillet over medium heat until browned

  3. 3

    Drain fat from beef

  4. 4

    Add pizza sauce, bell peppers, and onions to skillet

  5. 5

    Cook mixture for 5 minutes

  6. 6

    Pour mixture into baking dish

  7. 7

    Top with shredded mozzarella cheese

  8. 8

    Place refrigerated biscuits on top of cheese

  9. 9

    Bake for 20-25 minutes until biscuits are golden brown

Tips

Tip 1

Drain ground beef thoroughly to prevent a greasy casserole that could make the biscuits soggy.

Tip 2

Use a deep baking dish to accommodate the biscuits expanding as they bake on top of the filling.

Tip 3

Let casserole rest 5 minutes after baking so the cheese sets and makes serving easier.

Good to Know

Storage

Cover and refrigerate up to 3 days. Reheat in 350°F oven until warmed through.

Make Ahead

Assemble casserole without biscuits up to 1 day ahead. Add biscuits just before baking.

Serve With

Serve hot directly from baking dish. Pairs well with simple green salad.

See pairing guide →

Common Mistakes

Watch

Drain beef fat thoroughly to avoid greasy casserole.

Watch

Use deep enough dish to prevent overflow as biscuits rise.

Watch

Don't overbake or biscuits become dry and tough.

Substitutions

ground beef
ground turkey1:1leaner

reduces fat content

Full guide →
pizza sauce
marinara sauce1:1basic

similar flavor profile

Full guide →
mozzarella cheese
cheddar cheese1:1flavor

sharper taste

Full guide →
refrigerated biscuits
frozen biscuits1:1convenience

thaw first

Find more substitutions →

FAQ

Can I use fresh biscuits instead of refrigerated?

Yes, homemade biscuits work well. Drop spoonfuls of biscuit dough on top instead of placing whole biscuits.

What if I don't have pizza sauce?

Marinara sauce or even tomato sauce with Italian seasoning makes a good substitute with similar results.

How long does this keep in the refrigerator?

Covered leftovers stay fresh for up to 3 days. Reheat portions in microwave or whole dish in oven.