Instant Pot Mississippi Pot Roast with Ranch and Pepperoncini

Prep: 10 minCook: 1 hr 10 min6 servingsmediumAmerican
Instant Pot Mississippi Pot Roast with Ranch and Pepperoncini

A tender, fall-apart chuck roast cooked in pressure cooker with tangy pepperoncini peppers, rich butter, and savory ranch seasoning. The combination creates a flavorful, comfort-food favorite that's perfect for busy weeknight dinners or Sunday family meals. This simplified version delivers restaurant-quality results in just over an hour, with minimal prep work required. The pepperoncini juice and beef broth create a delicious au jus that pairs perfectly with mashed potatoes or crusty bread.

Ingredients

6 servings
  • 3 pounds Chuck Roast
    beef brisket1:1none

    longer cook time needed

    Full guide →
  • 1 packet ranch seasoning mix, 1 ounce packet
    onion soup mix1:1gluten-freemsg-free

    slightly different flavor profile

  • ½ cup butter, 1 stick
    olive oil1:2 ratiodairy-freepaleodairy-free

    less rich flavor

    Full guide →
  • ½ jar Pepperoncini Peppers with the Juice, 16 ounces
    banana peppers1:1none

    milder heat level

  • ½ cup Beef Broth

Instructions

  1. 1

    Place roast in bottom of instant pot

  2. 2

    Sprinkle ranch mix over the roast

  3. 3

    Place butter on top and pour pepperoncini with juice over it

  4. 4

    Pour beef broth around the roast

  5. 5

    Add lid and turn to sealing, set manual button to 70 minutes

  6. 6

    Allow pressure to release naturally for 15 minutes then quick release remaining pressure

  7. 7

    Shred beef with 2 forks and stir back into sauce

  8. 8

    Serve warm

Tips

Tip 1

Let meat come to room temperature before cooking for more even results

Tip 2

Save the cooking liquid as a flavorful au jus for serving over mashed potatoes

Tip 3

For extra flavor, sear the roast in the instant pot using saute function before adding other ingredients

Good to Know

Storage

Refrigerate up to 4 days in covered container

Make Ahead

Can be made 2 days ahead, reheat gently with additional broth if needed

Serve With

Serve hot over mashed potatoes, rice, or with crusty bread

See pairing guide →

Common Mistakes

Watch

Don't skip natural pressure release or meat will be tough

Watch

Avoid opening lid during cooking time or pressure will be lost

Watch

Don't add too much liquid or flavors will be diluted

Substitutions

Dairy-Free Swaps

butter
olive oil1:2 ratiodairy-freepaleodairy-free

less rich flavor

Full guide →

Gluten-Free Swaps

ranch seasoning mix
onion soup mix1:1gluten-freemsg-free

slightly different flavor profile

General Alternatives

chuck roast
beef brisket1:1none

longer cook time needed

Full guide →
pepperoncini
banana peppers1:1none

milder heat level

Find more substitutions →

FAQ

Can I use a different cut of meat for this recipe?

Yes, beef brisket or bottom round roast work well, though cooking times may need adjustment. Chuck roast is preferred for its marbling and tenderness.

What if I don't have an Instant Pot?

Use a slow cooker on low for 8 hours or oven braise at 325F for 3-4 hours in covered Dutch oven with same ingredients.

How long will leftovers keep in the refrigerator?

Properly stored leftovers will keep 3-4 days refrigerated. Reheat gently with a splash of broth to maintain moisture and prevent drying out.