Keto Sheet Pan Italian Meatloaf with Mozzarella and Pizza Sauce

This sheet pan meatloaf combines ground beef and Italian sausage with aromatic vegetables and herbs, topped with sugar-free pizza sauce and melted mozzarella cheese. The recipe uses keto bread crumbs as a binder instead of traditional breadcrumbs, keeping it low-carb friendly. Perfect for meal prep or feeding a crowd, this version bakes on a large sheet pan for easy portioning and cleanup. The broiled cheese topping creates a golden, bubbly finish reminiscent of pizza flavors in meatloaf form.
Ingredients
- ½ batch 90-Second Keto bread, prepared per step 1
- 1 tablespoon extra-virgin olive oil
- ½ cup onion, finely diced
- ½ cup green bell pepper, finely diced
- 1 tablespoon fresh garlic, minced fine
- 2 pounds 80/20 ground beef
- 1 pound Italian mild sausage, out of casing
- 3 eggs, beaten
- 2 teaspoons kosher salt
- ½ teaspoon freshly ground black pepper
- 1 teaspoon dry oregano
- 1 teaspoon dry basil
- ¼ cup freshly grated Parmesan cheese
- 2 cups Easy No-Cook Pizza Sauce, made without sugar
- 3 cups shredded mozzarella cheese
Instructions
- 1
Make half batch of 90-second keto bread in microwave-safe pie plate for 2-3 minutes until no longer liquid
- 2
Preheat oven to 375 degrees F
- 3
Saute onion, peppers and garlic in olive oil over medium heat for four minutes then cool
- 4
Mix ground beef, sausage, eggs, salt, pepper, oregano, basil, Parmesan and cooled vegetables in large bowl
- 5
Crumble keto bread into mixture and work in thoroughly
- 6
Press meat mixture into sprayed 17 1/2 X 12 1/2-inch sheet pan
- 7
Spread pizza sauce over top leaving edges exposed
- 8
Bake for 10 minutes then remove pooled fat with turkey baster
- 9
Bake 5 more minutes and remove fat again without tilting pan
- 10
Switch oven to broil setting
- 11
Top with mozzarella cheese and broil until browned and bubbly
- 12
Remove remaining fat, cut into 12 portions and serve
Tips
Use a turkey baster to remove pooled fat during baking to prevent greasiness and help cheese adhere properly.
Don't tilt the pan to drain fat as this may cause the pizza sauce to slide off the meatloaf.
The keto bread can be prepared a day in advance and refrigerated until ready to use.
Good to Know
Refrigerate leftovers up to 4 days in airtight container. Reheat individual portions in microwave or oven.
Keto bread component can be made 1 day ahead. Assembled meatloaf can be prepared and refrigerated up to 4 hours before baking.
Cut into 12 portions (4x3 grid). Serve hot with side salad or roasted vegetables.
Common Mistakes
Don't skip fat removal steps or meatloaf will be greasy
Avoid tilting pan to drain fat as sauce will slide off
Substitutions
FAQ
Can I freeze this meatloaf?
Yes, wrap cooled portions individually and freeze up to 3 months. Thaw overnight in refrigerator before reheating.
What if I don't have a sheet pan this size?
Use a 9x13 baking dish but increase cooking time by 5-10 minutes since it will be thicker.
Can I make this without the keto bread?
Yes, substitute with almond flour or omit entirely, though texture will be slightly different.