Mediterranean Grilled Cheese with Prosciutto and Artichokes
A gourmet twist on classic grilled cheese featuring savory prosciutto, tangy artichoke hearts, fresh tomatoes, and melted cheese on buttery sandwich bread. The Mediterranean flavors create a sophisticated comfort food perfect for lunch or dinner. Served alongside roasted broccoli with balsamic and lemon, this sandwich transforms simple ingredients into a restaurant-quality meal that's both satisfying and flavorful.
Ingredients
Instructions
- 1
Heat oven to 425F
- 2
Toss broccoli with red pepper flakes, balsamic vinegar, cooking oil, salt and pepper
- 3
Spread broccoli onto sheet pan and roast for 20 minutes, shaking once and rotating pan midway through
- 4
Butter one side of each bread slice
- 5
Lay bread buttered-side down and layer with cheese, prosciutto, tomatoes, artichokes, another slice of cheese and top with bread buttered-side up
- 6
Heat griddle or skillet over medium heat
- 7
Place sandwiches onto heated surface and press down with spatula throughout grilling
- 8
Flip once first side is golden, about 3 to 4 minutes
- 9
Finish roasted broccoli with lemon juice, salt and pepper
- 10
Serve hot grilled cheese with roasted broccoli
Tips
Press sandwiches firmly with spatula while grilling to ensure even browning and melted cheese throughout.
For lower calorie option, make open-face melts by halving cheese and bread, then broiling for 4-6 minutes.
Shake and rotate the broccoli pan midway through roasting for even caramelization.
Good to Know
Refrigerate assembled uncooked sandwiches up to 4 hours. Store roasted broccoli separately up to 3 days.
Prep vegetables and assemble sandwiches up to 4 hours ahead. Roast broccoli day before and reheat.
Serve immediately while cheese is melted and bread is crispy. Cut sandwiches diagonally for easier eating.
Common Mistakes
Use medium heat to avoid burning bread before cheese melts
Press sandwiches gently to avoid squeezing out filling
Don't overcrowd pan when grilling multiple sandwiches
Substitutions
FAQ
Can I make these sandwiches ahead of time?
Assemble sandwiches up to 4 hours ahead and refrigerate. Grill just before serving for best texture and melted cheese.
What if I don't have a griddle or large skillet?
Use a regular skillet and cook sandwiches in batches. Keep finished sandwiches warm in 200F oven while cooking remaining ones.
How long will leftover roasted broccoli keep?
Store roasted broccoli in refrigerator up to 3 days. Reheat in oven at 350F for 5-7 minutes to restore crispness.