Pizza-Stuffed Pasta Shells with Ground Beef and Pepperoni
These jumbo pasta shells are generously filled with seasoned ground beef and pepperoni, then smothered in pizza sauce and melted mozzarella cheese. The result is a comforting casserole that captures all the flavors of pizza in pasta form. Perfect for family dinners or feeding a crowd, this hearty dish combines the best of Italian-American comfort food. Each shell delivers a satisfying bite of meaty filling wrapped in tender pasta, making it especially appealing to kids and adults alike.
Ingredients
Instructions
- 1
Heat oven to 375°F
- 2
Spray 13x9-inch glass or ceramic baking dish with cooking spray
- 3
Cook ground beef and garlic in nonstick skillet over medium-high heat for 5 to 7 minutes, stirring occasionally, until thoroughly cooked
- 4
Drain beef mixture
- 5
Stir in half of the pepperoni slices and 1 cup pizza sauce into beef mixture
- 6
Cook for 5 minutes until thoroughly heated
- 7
Remove from heat
- 8
Cook pasta shells as directed on package
- 9
Drain pasta shells
- 10
Stuff each shell with 2 tablespoons beef mixture
- 11
Place stuffed shells in single layer in prepared baking dish
- 12
Cover shells with remaining pizza sauce, mozzarella cheese, and remaining pepperoni
- 13
Bake for 25 minutes until bubbly and cheese is melted
- 14
Let stand 5 minutes before serving
Tips
Use a spoon or small scoop to evenly fill shells with beef mixture for consistent portions
Let the casserole rest for 5 minutes after baking to help the shells hold their shape when serving
Cook pasta shells just until al dente since they will continue cooking in the oven
Good to Know
Refrigerate leftovers for up to 3 days in covered container
Assemble casserole up to 1 day ahead, cover and refrigerate, then bake as directed adding 5-10 minutes
Serve hot directly from baking dish with garlic bread or side salad
Common Mistakes
Cook shells just until al dente to avoid mushy texture after baking
Drain ground beef thoroughly to prevent watery casserole
Let stand 5 minutes before serving to prevent shells from falling apart
Substitutions
FAQ
Can I freeze this casserole?
Yes, assemble without baking, wrap tightly and freeze up to 3 months. Thaw overnight in refrigerator and bake as directed, adding 10-15 minutes to cook time.
What if I can't find jumbo shells?
Use large shells instead and reduce filling to 1 tablespoon per shell, or substitute with cooked ziti or rigatoni for a different presentation.
Can I make this ahead for a party?
Absolutely. Assemble the casserole up to 24 hours in advance, cover and refrigerate, then bake when ready to serve.